Top 25 College Hoops Picks Against the Spread – Saturday, December 21

Published 7:31 pm Friday, December 20, 2024

Top-25 teams will hit the court across 15 games on Saturday’s college basketball slate. That includes the Purdue Boilermakers playing the Auburn Tigers at Legacy Arena at BJCC. Looking for against-the-spread picks? You’ve come to the right place.

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AP Top 25 Picks ATS Today

No. 7 Florida Gators vs. North Florida Ospreys

Spread Prediction

  • Computer Prediction: Florida 89, North Florida 72
  • Projected Favorite: Florida by 16.3 points
  • Pick ATS: North Florida (+26.5)

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Bet on the Florida-North Florida spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 12:00 PM ET
  • Location: Gainesville, Florida
  • Venue: Exactech Arena at the Stephen C. O’Connell Center
  • TV Channel: SEC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Xavier Musketeers vs. No. 9 Marquette Golden Eagles

Spread Prediction

  • Computer Prediction: Marquette 77, Xavier 72
  • Projected Favorite: Marquette by 5.4 points
  • Pick ATS: Marquette (-4.5)

Bet on the Xavier-Marquette spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 12:00 PM ET
  • Location: Cincinnati, Ohio
  • Venue: Cintas Center
  • TV Channel: FOX
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Butler Bulldogs vs. No. 11 UConn Huskies

Spread Prediction

  • Computer Prediction: UConn 74, Butler 72
  • Projected Favorite: UConn by 1.6 points
  • Pick ATS: Butler (+9.5)

Bet on the Butler-UConn spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 12:00 PM ET
  • Location: Indianapolis, Indiana
  • Venue: Hinkle Fieldhouse
  • TV Channel: Peacock
  • Live Stream: Peacock

Georgia Tech Yellow Jackets vs. No. 5 Duke Blue Devils

Spread Prediction

  • Computer Prediction: Duke 78, Georgia Tech 66
  • Projected Favorite: Duke by 12.5 points
  • Pick ATS: Georgia Tech (+15.5)

Bet on the Georgia Tech-Duke spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 12:00 PM ET
  • Location: Atlanta, Georgia
  • Venue: Hank McCamish Pavilion
  • TV Channel: ACC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 21 Memphis Tigers vs. Mississippi State Bulldogs

Spread Prediction

  • Computer Prediction: Memphis 77, Mississippi State 76
  • Projected Favorite: Memphis by 0.9 points
  • Pick ATS: Memphis (+1.5)

Bet on the Memphis-Mississippi State spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 12:30 PM ET
  • Location: Memphis, Tennessee
  • Venue: FedExForum
  • TV Channel: CBS
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 15 Houston Cougars vs. Texas A&M-CC Islanders

Spread Prediction

  • Computer Prediction: Houston 82, Texas A&M-CC 60
  • Projected Favorite: Houston by 22.3 points
  • Pick ATS: Texas A&M-CC (+30.5)

Bet on the Houston-Texas A&M-CC spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 2:00 PM ET
  • Location: Houston, Texas
  • Venue: Fertitta Center
  • TV Channel: CBS Sports Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 20 Michigan State Spartans vs. Florida Atlantic Owls

Spread Prediction

  • Computer Prediction: Michigan State 85, Florida Atlantic 72
  • Projected Favorite: Michigan State by 12.4 points
  • Pick ATS: Florida Atlantic (+12.5)

Bet on the Michigan State-Florida Atlantic spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 2:00 PM ET
  • Location: East Lansing, Michigan
  • Venue: Jack Breslin Students Events Center
  • TV Channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 25 Clemson Tigers vs. Wake Forest Demon Deacons

Spread Prediction

  • Computer Prediction: Clemson 75, Wake Forest 64
  • Projected Favorite: Clemson by 10.9 points
  • Pick ATS: Clemson (-8.5)

Bet on the Clemson-Wake Forest spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 2:00 PM ET
  • Location: Clemson, South Carolina
  • Venue: Littlejohn Coliseum
  • TV Channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

North Carolina Tar Heels vs. No. 18 UCLA Bruins

Spread Prediction

  • Computer Prediction: UCLA 76, North Carolina 75
  • Projected Favorite: UCLA by 1.3 points
  • Pick ATS: North Carolina (+1.5)

Bet on the North Carolina-UCLA spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 3:00 PM ET
  • Location: New York City, New York
  • Venue: Madison Square Garden
  • TV Channel: CBS
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 2 Auburn Tigers vs. No. 16 Purdue Boilermakers

Spread Prediction

  • Computer Prediction: Auburn 80, Purdue 70
  • Projected Favorite: Auburn by 10 points
  • Pick ATS: Purdue (+10.5)

Bet on the Auburn-Purdue spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 4:30 PM ET
  • Location: Birmingham, Alabama
  • Venue: Legacy Arena at BJCC
  • TV Channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 17 Ole Miss Rebels vs. Queens Royals

Spread Prediction

  • Computer Prediction: Ole Miss 85, Queens 63
  • Projected Favorite: Ole Miss by 21.8 points
  • Pick ATS: Queens (+27.5)

Bet on the Ole Miss-Queens spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 5:00 PM ET
  • Location: Oxford, Mississippi
  • Venue: The Sandy and John Black Pavilion at Ole Miss
  • TV Channel: SEC Network+
  • Live Stream: SEC Network+

No. 4 Kentucky Wildcats vs. Ohio State Buckeyes

Spread Prediction

  • Computer Prediction: Kentucky 81, Ohio State 75
  • Projected Favorite: Kentucky by 5.8 points
  • Pick ATS: Ohio State (+7.5)

Bet on the Kentucky-Ohio State spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 5:30 PM ET
  • Location: New York City, New York
  • Venue: Madison Square Garden
  • TV Channel: CBS
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Stanford Cardinal vs. No. 10 Oregon Ducks

Spread Prediction

  • Computer Prediction: Oregon 76, Stanford 71
  • Projected Favorite: Oregon by 4.8 points
  • Pick ATS: Stanford (+5.5)

Bet on the Stanford-Oregon spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 8:00 PM ET
  • Location: San Jose, California
  • Venue: SAP Center at San Jose
  • TV Channel: BTN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 13 Gonzaga Bulldogs vs. Bucknell Bison

Spread Prediction

  • Computer Prediction: Gonzaga 91, Bucknell 62
  • Projected Favorite: Gonzaga by 29.1 points
  • Pick ATS: Bucknell (+34.5)

Bet on the Gonzaga-Bucknell spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 9:00 PM ET
  • Location: Spokane, Washington
  • Venue: McCarthey Athletic Center
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

No. 23 San Diego State Aztecs vs. California Golden Bears

Spread Prediction

  • Computer Prediction: San Diego State 78, Cal 70
  • Projected Favorite: San Diego State by 8.1 points
  • Pick ATS: San Diego State (-4.5)

Bet on the San Diego State-Cal spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 10:30 PM ET
  • Location: San Jose, California
  • Venue: SAP Center at San Jose
  • TV Channel: ACC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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