There are several strong matchups on Friday in SEC action, including a Pittsburgh Panthers playing the LSU Tigers. If you’re interested in predictions against the spread, continue reading.

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SEC Picks ATS Today

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Pick: Pittsburgh -5.5 vs. LSU

• Matchup: Pittsburgh Panthers vs. LSU Tigers
• Projected Favorite & Spread: Pittsburgh by 18.7 points (Bet on BetMGM)
• Spread: Pittsburgh -5.5
• Time: 2:30 PM ET
• Date: November 22
• TV Channel: CBS Sports Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Pick: Southern Illinois +18 vs. Florida

• Matchup: Southern Illinois Salukis at Florida Gators
• Projected Favorite & Spread: Florida by 6.0 points (Bet on BetMGM)
• Spread: Florida -18
• Time: 7:00 PM ET
• Date: November 22
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Pick: Jackson State +34.5 vs. Kentucky

• Matchup: Jackson State Tigers at Kentucky Wildcats
• Projected Favorite & Spread: Kentucky by 30.6 points (Bet on BetMGM)
• Spread: Kentucky -34.5
• Time: 7:00 PM ET
• Date: November 22
• TV Channel: SEC Network+

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Pick: Missouri -19 vs. Pacific

• Matchup: Pacific Tigers at Missouri Tigers
• Projected Favorite & Spread: Missouri by 22.9 points (Bet on BetMGM)
• Spread: Missouri -19
• Time: 7:30 PM ET
• Date: November 22
• TV Channel: SEC Network+

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Pick: Little Rock +21.5 vs. Arkansas

• Matchup: Little Rock Trojans at Arkansas Razorbacks
• Projected Favorite & Spread: Arkansas by 15.2 points (Bet on BetMGM)
• Spread: Arkansas -21.5
• Time: 9:00 PM ET
• Date: November 22
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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